I just read in my new edition of the Windows Internals part 1 book that versions of W10 that support Hyper-V now also support a new Virtualization based security architecture.
With this model the OS, both user and kernel mode portions, is split into two parts called Virtual trust levels 1 and 2. Both VTL0 and VTL1 run as separate Hyper-V virtual machines with the most secure sections running on VTL1.
I would like to have a play with this but I only have W10 home where I am so I can’t 😬. Apparently it shows up under Add Windows Features as Isolated User Mode if you would like to see if your system is using it.
You will also need a fairly recent CPU that supports Second Level Address Translation and an I/O MMU.